A postdoctoral research fellow position is available for 3-years at CRCT (Toulouse Cancer Research Center) in Corinne Bousquet’s Research group « Microenvironment & Therapeutic Resistance in Pancreatic Neoplasms. »
The project aims at understanding pancreatic cancer heterogeneity in spatial cell positioning, focusing on the interplay between cancer cells, cancer-associated fibroblasts and immune cells, to understand immune cell exclusion within sub-tumor microenvironment areas. Within an European Consortium (Belgium, Spain, Italy & France), the role of specific guidance cues that may organize cell attraction or repulsion will be explored. To do so, multiplex RNA and protein immunohistofluorescence on pancreatic cancer tissue shall be developed, as well as functional assays using 3D cell co-cultures.
Toulouse is a dynamic research area located in south of France that comprises many internationally recognized laboratories (fundamental cell biology, pharmacology, cancerology, immunology, metabolism, agronomy…) and gives access to a network of highlevel skills research platforms in life sciences (GENOTOUL – Un ensemble de ressources au service de la R&D, e.g. imaging, cytometry, bioinformatics, genomics & transcriptomics,
biostatistics ; Metatoul – Home (inrae.fr), e.g. metabolomics & fluxomics; Toulouse Proteomics Infrastructure | IPBS, e.g. proteomics) making possible almost all research projects.
The Toulouse Cancer Research Center, accredited by INSERM, CNRS and Toulouse University, is internationally recognized and offers a productive scientific environment centered on basic, transdisciplinary (bioinformatics, mathematics & physics in close link with the Toulouse Laboratoire d’analyse et d’architecture des systèmes | LAAS-CNRS and Laboratoire de Physique et Chimie des Nano-objets (insa-toulouse.fr)), and clinical research (in close link with the IUCT Oncopole – Institut Universitaire du Cancer de Toulouse – Accueil (iuct-oncopole.fr)), to understand and treat cancers. CRCT brings together a total of >250 Researchers, MDs, University Professors, Technicians, Students and Post-docs of many nationalities. CRCT offers on-site state-of-the-art technological platforms with personalized project support, including single cell RNAseq (Le pôle technologique DU CRCT – Centre de
Recherches en Cancérologie de Toulouse (crct-inserm.fr)).